2005 IRISH SCIENTIST YEAR BOOK

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University College Dublin and St Vincent's University Hospital

Cliona O'Farrelly
Translational research at St. Vincent's University Hospital: the path to new cures






St. Vincent's University Hospital (SVUH) is renowned for its commitment to biomedical research with the ultimate goal of improving patient care. With dedicated laboratory and clinical research facilities, SVUH based research programmes complement the primary clinical, diagnostic and treatment challenges in Ireland today. In particular, research into cancer, arthritis, respiratory disease and liver disease is now integral to care of patients with these diseases. SVUH, in collaboration with the Conway Institute at UCD and the Dublin Molecular Medicine Centre, has taken the lead to accelerate translational research in Ireland. The combined scientific and clinical teams strive to translate the exciting research discoveries into new treatments and cures for these debilitating diseases.


Patricia McGowan and Brid Ryan are part of the Breast Cancer Research Group, led by Prof. Joe Duffy, which has identified important new prognostic markers

The research reputation of SVUH is based on secure foundations now being used to catapult translational research into the 21st Century. Several million euro in research funds have been raised by SVUH researchers from government, pharmaceutical and charitable sources to support well defined research programmes. More than 400 publications have been published in international peer-reviewed journals and many medical, surgical and science graduates have received higher degrees in biomedical subjects. At the moment, over 40 science and medical graduates based at SVUH are registered for higher degrees and more than 30 of the hospital's consultants are actively engaged in translational research.


Margaret O'Brien is a Medical Student & Post Doctoral Researcher. Her research aims to determine how the immune response affects outcome in malignancy.

Significant national and international honours have been awarded to SVUH clinical and scientific investigators, who are also regularly invited to speak at high profile international meetings. National and international research collaborations have been established with SUVH scientific and clinical investigators. Some of these collaborations have been initiated from our annual research symposium entitled 'Common Molecular Mechanisms of Inflammation and Malignancy'.


Translational Research is dependent on careful long term storage and documentation of patient samples as well as combined clinical and scientific expertise


Contact: Professor Cliona O'Farrelly,
Director, Research Laboratories, Education and Research Centre,
St Vincent's University Hospital,
Dublin 4; Tel: 01-277 4940; Fax: 01-283 8123;
E-mail: [email protected]